Ability of models to reproduce the experimental situation to observe (Part I)

To put it short and understandable Mexican Professor A. Rosenblueth and Norbert Wiener, the latter considered the father of cybernetics, in an article published in 1945 coined the phrase which states: "The best model of a cat is a cat, and preferably the same cat. It is a philosophical definition of the ideal experimental model. That model or "model? that seeks to reproduce as nearly, if not all, the condition to be studied, the situation that occurs naturally, intervention or action or effect etiopathogenic and changes that occur in the model study.

It is a common and contrast with virtually no experimental model reproduces in full the conditions that occur naturally, and this is particularly true in medicine and life science research. However, there are models for almost all the processes that make up an institution which, studied or launched in a segmental able to provide information most useful to increase our knowledge.

Experimental models must meet certain requirements to be validated and provide adequate reliability as a reflection of the process to be studied. These conditions or requirements are summarized in the following criteria:

Face validity: refers to the ability of the model to reproduce the visible manifestations of the process and detectable estudiarValidez predictive or condition: The effect of the intervention will be playable on the natural condition or in the individual beneficiary shall the results. In other words, the effects are predictable pattern in the human or construct real.Validez situation: It is the criterion most difficult to achieve. It refers to reproduction in the model or the mechanisms involved in the process to be studied.

These criteria were expressed and established by Van der Staay FJ, SS Arndt, RE Nordquist. (Evaluation of animal models of neurobehavioral disorders. Behav.Brain Funct. 2009 Feb 25, 5:11) and O'Dell LE, Khroyan TV. (Rodent Models of Nicotine Reward: What Do They Tell us About tobacco abuse in Humans? Pharmacol Biochem Behav. 2009 Feb, 91 (4) :481-488)